Most common site of metastasis of gastric carcinoma is:
A. Liver
B. Lung
C. Bone
D. Brain
Answer: A (G+S)
Metastasis of gastric carcinoma
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- Hematogenous spread
- Liver (most common)
- Lung
- Skeleton
- Brain
- Lymphangitic spread
- Virchow node: left supraclavicular lymph node metastasis
- Sister Mary Joseph node: periumbilical lymph node metastasis (subcutaneous)
- Krukenberg tumor: metastatic tumor of the ovary cause by diffuse gastric cancer
- Celiac, paraaortic, and mesenteric lymph nodes
- Lymph nodes of the lesser and greater curvature
- Mediastinal lymph nodes (in carcinoma of the cardia)
- Local invasion of adjacent structures
- Peritoneal carcinomatosis (seeding of abdominal tumor to the peritoneum)
- Infiltration of structures such as the esophagus, pancreas and transverse colon.
- Direct seeding: Blumer shelf (direct seeding to the pouch of Douglas)
Blumer's shelf is a finding felt in rectal examination that indicates that a tumor has metastasized to the pouch of Douglas.

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